Tioconazole BP 300mg: vaginal suppository.
Tioconazole is a member of the imidazole class of antifungal agents.
Ind: Vulvo-vaginal candidiasis.
C/I: History of sensitization to tioconazole or to any of the other components of vaginal supposi¬tory or to other imidazole antifungal agents.
S/E: The most frequently observed local side- effects are burning (6%) and itching (5%).
Isolated local vaginal symptoms such as irritation, discharge, labial swelling, vaginal pain, dysuria, nocturia, dyspareunia, dryness of vaginal secretions, vulva edema are observed. Precautions: Constituents of the vaginal supposi¬tory may be incompatible with rubber in both contraceptive condoms and diaphragms. Skin and mucosal sensitization may occur. If so, use of tioconazole vaginal suppository should be discontinued.
Pregnancy & lactation: There are no adequate and well controlled studies which establish the safety of tioconazole vaginal suppository in preg¬nant women. So, the use of vaginal suppository during pregnancy should be considered only if the potential benefit outweighs the potential risk to the fetus.
Tioconazole should not be used by nursing women unless the potential benefit outweighs the possible risk.
Dosage & admin: One 300mg suppository to be used intravaginally as single dose, prefera¬bly at bedtime for one night only; for patients who are improved but not completely cured a second application may be effective if administered one week later.
Vaginal candidiasis may be accompanied by vulval infection. Therefore, concomitant local treatment with the tioconazole cream should be applied to the vulva and as far as the anal region once or twice daily for up to 7 days (as needed) is advisable. To treat the male partner, a small amount of cream should be applied onto the glans penis once or twice daily for up to 7 days as needed or to help prevent reinfection by the partner.
5's pack: 301.10 MRP