Each gram of povisep gyno gel contains povi¬done-iodine USP 100mg (i.e 10%). It is available as a pack of 30gm gel in tube with an applicator. Mode of action: Povidone-iodine is a complex of iodine and an organic polymer, povidone. This polymerization makes iodine complex superior to ordinary elemental iodine. It prolongs the germi¬cidal activity of iodine by liberating elemental iodine slowly. Consequently it has a lower toxicity than elemental iodine.
It gives rapid microbicidal activity against both gram-positive and gram-negative bacteria, proto¬zoa, viruses and fungi/yeasts. It is also sporicidal. It is the only microbicide with this broad spectrum of activity. It is non-staining, exerts prolong germicidal action and also active in the presence of soap, blood, serum, pus, mucosal secretions and water.
Ind: Povisep gyno gel is used for the manage¬ment of vaginitis due to candidal, trichomonal, non-specific or mixed infections & for pre-opera¬tive preparation of vagina.
C/I: Known or suspected iodine hypersensitivity. Regular use is contraindicated in patients and users with thyroid disorders (in particular nodular colloid goiter, endemic goiter and Hashimoto’s thyroiditis). The porduct is not recommended for pre-puberty children.
S/E: Povidone-iodine may cause hypersensitivity reactions and irritation of the skin and mucous membranes. Local application of povidone-iodine may produce systemic adverse reactions associat¬ed with iodine such as metabolic acidosis, hypernatremia & impairment of renal function, although severe reaction are rare & povidone-iodine is con¬sidered less irritant than that of elemental iodine. Precautions: Special caution is needed when regular applications to the patients with pre-exist¬ing renal insufficiency. If local irritation, redness or swelling develops, discontinue treattment. Pregnancy & lactation: Regular use of povi¬done-iodine should be avoided in pregnant women as absorbed iodine cab cross the placental barrier. Although no adverse effects have been reported from limited use. Caution should be rec¬ommended and therapeutic benefit must be bala¬nced against possible effects of the absorption of iodine on foetal thyroid function & development. Dosage & admin: Povisep gyno gel is only for intra-vaginal use for adults and the elderly women. Insert one applicatorful of gel (5gm) every night for up to 14 days. During insertion of applicator in to the vagina patient should lie down on her back with knees bent and put the applicator in to the vagina as far as one can. Then remove the applicator from vagina and wash all parts in soapy water, rinse well and dry completely. If menstruation occurs during treatment, it is important to continue treatment during the days of the period.
30gm tube x 1’s pack: 80.00 IP