Arocaine-A DC is a sterile dental cartridge that

contains articaine hydrochloride and epinephrine bitartrate in an aqueous solution. Each ml of the solution contains- articaine hydrochloride BP 40mg& epinephrine bitartrate USP equivalent to epinephrine 10mcg(l: 100,000).

Mode of action: Articaine is a local anesthetic of the amide type. Epinephrine, an adrenergic vasocontrictor, added to articaine which reduces bleeding during surgery, slows down the passage of articaine into the general circulation & thus ensures the prolonged maintenance of an active tissue concentration. The onset of anaesthesia after administration of articaine hydrochloride 4% with epinephrine (1:100,000) is about 3.5 minutes with a range of 1 to 6 minutes and the mean duration of anaesthesia is about 68 minutes with a range of 20 to 175 minutes.

Ind: Arocaine-A DC is indicated for local, infil¬trative or conductive anesthesia in both simple and complex dental and periodontal procedures. C/I: Known hypersensitivity to local anesthetics of the amide type, or in patients with known hypersensitivity to sodium metabisulphite.

S/E; Precautions: See the manufacturer’s literature.

Pregnancy & lactation: There are no adequate and well controlled studies in pregnant women. This product should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Articaine is excreted in human milk, caution should be exercised when this product is administered to a nursing mother.

Dosage & admin: The recommended dose of Arocaine-A DC for normal healthy adults, administered by submucosal infiltration and/or nerve block are given below: The above suggested volumes serve only as a guide. Other volumes may be used provided the total maximum recommended dose is not exceeded. For normal healthy adult, the maximum recommended dose of articaine hydro-chloride administered by submucosal infiltration and/or nerve block should not exceed 7mg/kg. For the children more than 4 years dose of articaine hydrochloride should not exceed 7mg/kg (0.175ml/kg) body weight. Children: Arocaine-A DC should not be used in children age below 4 years.

Drug inter: The administration of local anesthet¬ic solutions containing epinephrine to patients receiving monoamine oxidase inhibitors or tri¬cyclic antidepressants may produce severe, pro¬longed hypertension. Phenothiazines and buty- rophenones may reduce or reverse the pressor effect of epinephrine. Concurrent use of these agents should generally be avoided. In situations when concurrent therapy is necessary, careful patient monitoring is essential.

Price; 1.8ml cartridge x 5’s pack: 240.90 M|RP