Methyl Prednisolone Sodium Succcinate

When oral therapy is not feasible, and the strength, dosage form and route of administration of the drug reasonably lend the preparation to the treatment of the condition, this Sterile Powder is indicated for intravenous or intramuscular use in the following conditions:

Endocrine Disorders: Primary and secondary adrenocortical, Acute adrenocortical insufficiency preoperatively and in the event of serious trauma or illness, In patients with known adrenal insufficiency or when adrenocortical reserve is doubtful. Congenital adrenal hyperplasia, nonsuppurative thyroiditis, hypercalcaemia associated with cancer.

Anti - inflammatory treatment:

• Rheumatic Disorders: As adjunctive therapy for short term administration (to tide the patient over an acute episode or exacerbation) in: post – traumatic osteoarthritis, synovitis in osteoarthritis, rheumatoid arthritis, Including juvenile rheumatoid arthritis (Selected cases may require low – dose maintenance therapy), acute and Sub-acute bursitis, epicondylitis,acute non – specific tenosynovitis , acute gouty arthritis, psoriatic arthritis, ankylosing spondylitis.
• Collagen Diseases (Immune and complex Diseases): During an exacerbation or as maintenance therapy in selected cases of: systemic Iupus erythematosus (and Iupus nephritis) acute rheumatic carditis systemic dermatomyositis (polymyositis), polyarteritis nodosa, Good pasture’s syndrome.
• Dermatologic Diseases: Pemphigus, severe erythema multiforme (Stevens-Johnson syndrome), exfoliative dermatitis, bullous dermatitis herpetiformis, severe seborrhoeic dermatitis, severe psoriasis mycosis fungoides.
• Allergic States: Control of severe or incapacitating allergic conditions intractable to adequate trials of conventional treatment in : bronchial asthma, contact dermatitis, atopic dermatitis, serum sickness ,seasonal or perennial allergic rhinitis, drug hypersensitivity reactions, urticarial transfusion reactions, acute non – infectious laryngeal oedema (epinephrine is the drug of first choice).
• Opthalmic Diseases: Severe acute and chronic allergic and inflammatory processes involving the eye, such as: herpes zoster Opthalmicus, iritis, iridocyclitis, chorioretinitis, diffuse posterior uveitis and choroiditis optic neuritis, sympathetic ophathalmia, anterior segment inflammation, allergic conjunctivitis, allergic corneal marginal ulcers, and keratitis.
• Gastrointestinal Diseases: To tide the patient over a critical period of the disease in: ulcerative colitis (systemic therapy), regional enteritis (systemic therapy)
• Respiratory Diseases: Symptomatic sarcoidosis, berylliosis, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate anti-tuberculous chemotherapy, loeffler’s Syndrome not manageable by other means, aspiration pneumonitis.
• Edematous States: To induce dieresis or remission of proteinuria in the nephritic syndrome, without uremia,of the idiopathic type or that due to lupus erythematosus. Immunosuppressive Treatment: Organ Transplantation.